Follistatin-344 1mg

Product Overview

Follistatin-344 (FST-344) is a naturally occurring glycoprotein isoform belonging to the follistatin protein family and is widely studied for its interaction with myostatin, activin, and related members of the TGF-β signaling superfamily.

Within laboratory research environments, this protein is frequently used to investigate cellular growth regulation mechanisms, protein-mediated signaling pathways, and molecular interactions between regulatory growth factors.

The 344-amino-acid isoform represents the precursor form of follistatin and is commonly used in experimental models to study regulatory protein processing and signaling behavior.

Understanding Follistatin-344

Follistatin proteins function as regulatory molecules that bind to activin and myostatin signaling proteins within the TGF-β superfamily.

Researchers frequently investigate follistatin isoforms to better understand cellular growth regulation, differentiation signaling pathways, and regulatory protein interaction networks.

The FST-344 isoform serves as the precursor molecule that can be processed into shorter circulating isoforms such as Follistatin-315.

Recombinant proteins like Follistatin-344 provide clearly defined molecular tools that enable controlled and reproducible biochemical and molecular biology research.

Mechanistic Research Perspective

• Myostatin binding and inhibition pathway studies
• Activin interaction and regulatory signaling analysis
• TGF-β pathway modulation research
• Protein-protein interaction investigations
• Cellular growth regulation and differentiation signaling studies

Primary Research Applications

Cellular and Molecular Biology Research: Used to explore regulatory protein signaling pathways and growth factor mediated cellular mechanisms.

Protein Interaction Studies: Supports investigation of activin and myostatin binding interactions within signaling pathways.

Growth Factor Regulation Research: Applied in experimental models examining signaling systems within the TGF-β pathway.

Biochemical Assay Development: Used in receptor-binding experiments and controlled in-vitro biochemical assays.

Comparative Isoform Research: Researchers compare follistatin isoforms such as FST-344 and FST-315 to evaluate regulatory signaling behavior.

Molecular Characteristics

• Protein Type: Recombinant regulatory glycoprotein
• Isoform: Follistatin-344 (FST-344)
• Amino Acid Length: 344 amino acids
• Structure: Recombinant protein isoform
• Form: Lyophilized powder
• CAS Identifier: Not assigned

Storage and Handling Guidelines

• Store lyophilized protein at −20°C for optimal stability
• Avoid repeated freeze-thaw cycles
• Protect from moisture and direct light exposure
• Handle using appropriate sterile laboratory procedures
• Reconstitute under controlled laboratory conditions

Solubility and Laboratory Compatibility

• Sterile laboratory buffers
• Bacteriostatic water
• Physiological saline solutions
• Standard biochemical assay buffers

Product Specifications

Manufacturing and Analytical Verification

• Controlled recombinant protein expression
• High-resolution purification processes
• High-performance liquid chromatography (HPLC) purity verification
• Mass spectrometry molecular confirmation
• Batch-to-batch consistency validation

Regulatory Status

Follistatin-344 supplied by Bio-Peptides is intended strictly for laboratory research use only. This product is not approved for human consumption, veterinary use, medical treatment, or therapeutic development. Responsibility for regulatory compliance lies with the purchasing research institution.

Frequently Asked Questions