IGF-1 LR3 1mg
CAS: 946870-92-4
IGF-1 LR3 1mg by BioPeptide is a high-purity, research-grade insulin-like growth factor analog designed for advanced laboratory studies in IGF-1 receptor signaling, cellular growth regulation, and molecular pathway analysis. Engineered with an extended amino-acid sequence for enhanced receptor affinity and stability, this peptide is purified to ≥99% HPLC and identified by CAS 946870-92-4. Widely used in controlled in-vitro research across Europe and the United States, BioPeptide provides secure access to premium research peptides with verified documentation and professional laboratory packaging.
$215.00
Research Use Only
Research Overview
IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 engineered to enhance receptor binding and extend molecular stability.
In laboratory environments it is widely studied for IGF-1 receptor activation, cellular growth regulation, and intracellular signaling pathways.
The LR3 modification reduces interaction with IGF-binding proteins, allowing researchers to study prolonged receptor activation dynamics.
These properties make IGF-1 LR3 valuable for growth-factor signaling studies and molecular pathway investigation.
Scientific Background
Insulin-like growth factor-1 (IGF-1) plays a central role in regulating cell growth, differentiation, and metabolic activity.
Modified analogs such as IGF-1 LR3 are engineered to improve receptor interaction and signaling stability.
The LR3 modification reduces binding to IGF-binding proteins and increases the peptide’s effective signaling duration.
Because of these characteristics, IGF-1 LR3 is widely used in receptor-binding and intracellular signaling research models.
Mechanistic Research Perspective
- IGF-1 receptor activation studies
- Cell growth and proliferation signaling analysis
- PI3K/Akt and MAPK pathway investigation
- Growth factor signaling research
- Protein–receptor interaction modeling
Primary Research Applications
IGF-1 Receptor Signaling Studies: Researchers study receptor activation strength and duration using IGF-1 LR3 in controlled laboratory models.
Cell Proliferation & Growth Research: IGF-1 LR3 is frequently used in cell-based assays analyzing regulated cellular growth and proliferation pathways.
Molecular Signaling Pathway Analysis: Scientists investigate intracellular pathways such as PI3K/Akt and MAPK involved in growth factor signaling.
Cellular & Molecular Biology Research: Laboratories apply IGF-1 LR3 in in-vitro experiments studying transcriptional responses and intracellular signaling cascades.
In-Vitro Research Models: IGF-1 LR3 is widely used in controlled research models examining growth-factor behavior and receptor-mediated cellular responses.
Molecular Characteristics
- Compound Name: IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1)
- CAS Number: 946870-92-4
- Peptide Length: 83 amino acids
- Molecular Formula: C400H625N111O115S9
- Molecular Weight: ~9110 g/mol
- Form: Lyophilized peptide powder
- Purity: ≥99% HPLC verified
Stability Profile and Storage Recommendations
- Store lyophilized peptide at −20°C
- Protect from moisture and direct light exposure
- Avoid repeated freeze-thaw cycles
- Reconstituted solutions should be refrigerated
- Handle using aseptic laboratory techniques
Solubility and Reconstitution Options
- Sterile bacteriostatic water
- Sterile saline solutions
- Buffered aqueous laboratory solutions
- Biochemical assay buffers
- Laboratory-grade solvent systems
Technical Specifications
product Name
IGF-1 LR3 1mg
brand
BioPeptides
cas
946870-92-4
purity
≥99% (HPLC verified)
unit Size
1mg vial
form
Lyophilized powder
synthesis
Solid-Phase Peptide Synthesis (SPPS)
analytical
HPLC and Mass Spectrometry
molecular Structure
Modified insulin-like growth factor analog
stability
Stable when stored at −20°C
Analytical Validation and Quality Assurance
- High-performance liquid chromatography purity verification
- Mass spectrometry molecular weight confirmation
- Protein structural integrity validation
- Batch-to-batch analytical consistency testing
- Peptide stability verification
Frequently Asked Questions
IGF-1 LR3 is used to study IGF-1 receptor signaling, prolonged growth-factor activity, and downstream molecular pathways in controlled laboratory environments.
IGF-1 LR3 contains structural modifications that reduce binding to IGF-binding proteins and increase molecular stability, enabling prolonged receptor interaction.
Yes. IGF-1 LR3 is widely used in controlled in-vitro research models studying receptor signaling and cellular growth pathways.
The CAS number ensures accurate chemical identification, traceability, and reproducibility across laboratory documentation.
It is frequently used in cell biology, molecular signaling research, growth factor studies, and receptor-binding experiments.
The 1mg format allows precision experiments, minimizes peptide waste, and supports pilot receptor-binding studies.
Lyophilized IGF-1 LR3 should be stored at −20°C and protected from repeated freeze-thaw cycles.
BioPeptides provides high-purity peptide synthesis, verified CAS documentation, and laboratory-grade packaging for research institutions.