IGF-1 LR3 (Receptor Grade) 1mg
CAS: 946870-92-4
IGF-1 LR3 Receptor Grade 1mg by BioPeptide is a high-purity, research-grade insulin-like growth factor analog developed for advanced laboratory studies involving IGF-1 receptor signaling, cell proliferation pathways, and molecular growth regulation. Engineered with an extended amino-acid sequence for enhanced receptor affinity and stability, this peptide is purified to ≥99% HPLC and identified by CAS 946870-92-4. Widely used in controlled in-vitro and biochemical research across Europe and the United States, BioPeptide provides secure access to premium research peptides with verified documentation and professional laboratory packaging.
$245.00
Research Use Only
Research Overview
IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 engineered to enhance receptor affinity and biological stability.
In laboratory environments it is widely studied for IGF-1 receptor activation, cellular growth regulation, and intracellular signaling pathways.
The LR3 modification reduces interaction with IGF-binding proteins, allowing researchers to investigate prolonged receptor activation dynamics.
This makes IGF-1 LR3 valuable for studying molecular growth factor signaling and cellular proliferation mechanisms.
Scientific Background
Insulin-like growth factor-1 (IGF-1) is an important growth factor involved in cellular growth regulation and metabolic signaling.
Modified analogs such as IGF-1 LR3 are engineered to improve receptor binding efficiency and signaling duration.
These characteristics allow researchers to study growth factor signaling pathways in greater detail.
IGF-1 LR3 is frequently used in receptor-binding and molecular signaling research models.
Mechanistic Research Perspective
- IGF-1 receptor activation pathway research
- Cell proliferation signaling studies
- PI3K/Akt and MAPK pathway investigation
- Growth factor signaling analysis
- Protein–receptor interaction modeling
Primary Research Applications
IGF-1 Receptor Signaling Studies: Researchers study receptor activation strength and duration using IGF-1 LR3 in controlled experimental models.
Cell Growth & Proliferation Research: IGF-1 LR3 is frequently used in cell-based assays analyzing regulated cellular growth and proliferation pathways.
Molecular Signaling Pathway Analysis: Scientists investigate intracellular pathways such as PI3K/Akt and MAPK involved in growth factor signaling.
Cellular & Molecular Biology Research: Laboratories apply IGF-1 LR3 in in-vitro experiments studying transcriptional responses and intracellular signaling cascades.
In-Vitro Research Models: IGF-1 LR3 is widely used in controlled research models examining growth factor behavior and receptor-mediated cellular responses.
Molecular Characteristics
- Compound Name: IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1)
- CAS Number: 946870-92-4
- Peptide Length: 83 amino acids
- Molecular Formula: C400H625N111O115S9
- Molecular Weight: ~9110 g/mol
- Form: Lyophilized protein powder
- Purity: ≥99% HPLC verified
Stability Profile and Storage Recommendations
- Store lyophilized peptide at −20°C
- Protect from moisture and light exposure
- Avoid repeated freeze–thaw cycles
- Reconstituted solutions should be refrigerated
- Handle using aseptic laboratory techniques
Solubility and Reconstitution Options
- Sterile bacteriostatic water
- Sterile saline solutions
- Buffered laboratory solutions
- Biochemical assay buffers
- Laboratory-grade solvent systems
Technical Specifications
product Name
IGF-1 LR3 (Receptor Grade) 1mg
brand
BioPeptides
cas
946870-92-4
purity
≥99% (HPLC verified)
unit Size
1mg vial
form
Lyophilized protein powder
synthesis
Solid-Phase Peptide Synthesis (SPPS)
analytical
HPLC and Mass Spectrometry
molecular Structure
Modified insulin-like growth factor analog
stability
Stable when stored at −20°C
Analytical Validation and Quality Assurance
- High-performance liquid chromatography purity verification
- Mass spectrometry molecular weight confirmation
- Protein structural integrity validation
- Batch-to-batch analytical consistency testing
- Peptide stability verification
Frequently Asked Questions
IGF-1 LR3 contains structural modifications that enhance receptor affinity and molecular stability, allowing researchers to study prolonged receptor activation.
Receptor-grade IGF-1 LR3 provides high purity and consistency suitable for receptor-binding studies and molecular signaling experiments.
Yes. IGF-1 LR3 is widely used in controlled in-vitro research examining growth factor signaling and cellular response pathways.
The CAS number ensures accurate compound identification, traceability, and reproducibility across laboratory documentation.
It is widely used in cell biology, molecular signaling research, growth factor studies, and receptor-binding experiments.
The 1mg format allows precision experiments, minimizes peptide waste, and supports pilot studies or receptor-binding research.
Lyophilized IGF-1 LR3 should be stored at −20°C and protected from repeated freeze–thaw cycles.
BioPeptides provides high-purity synthesis, verified CAS documentation, and laboratory-grade packaging for research institutions.