LL-37 (CAP-18) 5mg
CAS: 154947-66-7
LL-37 (CAP-18) 5mg by BioPeptides is a high-purity antimicrobial research peptide developed for laboratory studies focused on innate immune signaling, host defense mechanisms, and peptide–membrane interactions. Produced using precision solid-phase peptide synthesis and purified to ≥99% HPLC, LL-37 provides excellent molecular accuracy and reproducibility for demanding scientific research environments.
$195.00
Research Use Only
Research Overview
LL-37 is a cationic antimicrobial peptide derived from the human cathelicidin precursor protein CAP-18.
Researchers study LL-37 for its role in innate immune defense and host–pathogen interaction mechanisms.
The peptide interacts with microbial membranes and immune signaling pathways in controlled laboratory models.
The 5mg research format supports extended experimental workflows and multiple microbiology or immunology assays.
Scientific Background
LL-37 is the only known human cathelicidin antimicrobial peptide identified in innate immune systems.
It plays a role in antimicrobial defense by interacting with bacterial membranes and modulating immune responses.
In research models, LL-37 is studied for its involvement in inflammatory signaling, immune cell recruitment, and epithelial barrier biology.
Because of its multifunctional behavior, LL-37 is widely used in microbiology and host-defense peptide research.
Mechanistic Research Perspective
- Antimicrobial peptide–membrane interaction studies
- Innate immune signaling pathway research
- Inflammatory signaling modulation research
- Host–pathogen interaction mechanisms
- Immune cell signaling and chemotaxis pathway studies
Primary Research Applications
Antimicrobial Mechanism Research: LL-37 is widely used in microbiology research to investigate antimicrobial peptide interactions with microbial membranes.
Innate Immunity Studies: Researchers study LL-37 to understand host defense signaling and immune response regulation.
Inflammatory Pathway Research: LL-37 supports investigation of inflammation-related signaling cascades and immune modulation mechanisms.
Cellular & Molecular Biology Research: Laboratories use LL-37 in cell-based assays to study peptide-mediated signaling and transcriptional responses.
Host–Pathogen Interaction Research: LL-37 is frequently used in studies exploring interactions between antimicrobial peptides and microbial systems.
Molecular Characteristics
- Compound Name: LL-37 (CAP-18)
- CAS Number: 154947-66-7
- Peptide Length: 37 amino acids
- Peptide Class: Human cathelicidin antimicrobial peptide
- Form: Lyophilized peptide powder
- Purity: ≥99% HPLC verified
- Unit Size: 5mg research format
Stability Profile and Storage Recommendations
- Store lyophilized peptide at −20°C
- Protect from moisture and direct light exposure
- Avoid repeated freeze–thaw cycles
- Reconstituted solutions should be refrigerated
- Prepare solutions using sterile laboratory solvents
Solubility and Reconstitution Options
- Sterile bacteriostatic water
- Sterile saline solution
- Buffered aqueous laboratory solutions
- Cell culture compatible buffers
- Biochemical assay solvent systems
Technical Specifications
product Name
LL-37 (CAP-18) 5mg
brand
BioPeptides
cas
154947-66-7
purity
≥99% (HPLC verified)
unit Size
5mg vial
form
Lyophilized powder
synthesis
Solid-phase peptide synthesis
analytical
HPLC and Mass Spectrometry
molecular Structure
37-amino acid antimicrobial peptide
stability
Stable when stored at −20°C
Analytical Validation and Quality Assurance
- High-performance liquid chromatography purity verification
- Mass spectrometry molecular weight confirmation
- Peptide structural integrity validation
- Batch-to-batch analytical consistency testing
- Peptide stability verification
Frequently Asked Questions
LL-37 is primarily studied for antimicrobial mechanisms, innate immune signaling, and host defense pathway research.
LL-37 combines antimicrobial membrane disruption with immune signaling modulation, allowing researchers to study both microbial interaction and host defense pathways.
CAS 154947-66-7 uniquely identifies LL-37, ensuring precise compound identification and reproducibility across laboratory research documentation.
Yes. LL-37 is widely used in microbiology studies investigating antimicrobial peptide activity and microbial membrane interaction.
LL-37 is commonly used in immunology, microbiology, molecular biology, antimicrobial research, and host–pathogen interaction studies.
The 5mg vial format allows multiple assays and extended research studies while minimizing peptide waste.
LL-37 should be stored at −20°C in lyophilized form and protected from moisture and repeated freeze–thaw cycles.
BioPeptides provides high-purity research peptides with verified CAS documentation and reliable shipping for research laboratories.