
Matrixyl® 200mg (Topical)
CAS: 214047-00-4
Matrixyl® (Palmitoyl Pentapeptide-4) 200mg Topical by BioPeptides is a high-purity, research-grade signal peptide formulated for advanced laboratory and formulation studies focused on extracellular matrix signaling, collagen-related pathways, and peptide–skin interaction research. Synthesized using precision solid-phase peptide synthesis and purified to ≥99% HPLC, this topical research material offers excellent molecular accuracy and reproducibility. Identified by CAS 214047-00-4, Matrixyl® is widely used in controlled in-vitro and formulation research across Europe and the United States.
$165.00
Research Use Only
Research Overview
Matrixyl® is a palmitoylated signal peptide derived from extracellular matrix protein fragments.
Researchers study this peptide for its interaction with dermal fibroblast signaling and collagen-associated pathways.
Its lipid-modified structure enables investigation of peptide–lipid interactions and topical peptide delivery models.
The 200mg research format supports extensive formulation testing and repeated laboratory experiments.

Scientific Background
Signal peptides play a role in regulating cellular communication within the extracellular matrix.
Palmitoyl Pentapeptide-4 mimics fragments of structural proteins involved in dermal matrix signaling.
In research environments, Matrixyl® is studied for its interaction with fibroblast signaling pathways and ECM-associated molecular communication.
Because of its lipid-conjugated structure, the peptide is also used in formulation research examining peptide stability and delivery behavior.
Mechanistic Research Perspective
- Extracellular matrix signaling pathway investigation
- Fibroblast cellular communication research
- Collagen-associated gene expression studies
- Peptide–lipid interaction models
- Topical peptide delivery system research
Primary Research Applications
Extracellular Matrix Signaling Studies: Matrixyl® is used to investigate ECM-related cellular communication pathways in dermal research models.
Collagen Pathway Research: Researchers study this peptide to explore signaling pathways associated with collagen gene expression and dermal matrix regulation.
Topical Formulation Research: The lipid-modified structure makes Matrixyl® useful in studies focused on peptide delivery systems and topical formulation stability.
Cellular & Molecular Biology Research: Laboratories use Matrixyl® in cell-based assays to examine signaling responses and molecular pathway behavior.
Peptide Delivery System Research: Matrixyl® is frequently incorporated into experimental topical formulations to investigate peptide transport and stability.
Molecular Characteristics
- Compound Name: Matrixyl® (Palmitoyl Pentapeptide-4)
- CAS Number: 214047-00-4
- Peptide Length: 5 amino acids
- Peptide Class: Lipopeptide signal peptide
- Form: Topical research peptide powder
- Purity: ≥99% HPLC verified
- Unit Size: 200mg research format
Stability Profile and Storage Recommendations
- Store refrigerated at 2–8°C
- Protect from direct light exposure
- Avoid moisture contamination
- Seal container tightly after use
- Handle using standard laboratory practices
Solubility and Preparation Considerations
- Compatible with cosmetic formulation solvents
- Soluble in peptide-compatible laboratory solvents
- Suitable for lipid-based formulation systems
- Compatible with buffered laboratory solutions
- Usable in topical formulation research protocols
Technical Specifications
product Name
Matrixyl® 200mg (Topical)
brand
BioPeptides
cas
214047-00-4
purity
≥99% (HPLC verified)
unit Size
200mg
form
Topical research peptide powder
synthesis
Solid-phase peptide synthesis (SPPS)
analytical
HPLC and mass spectrometry verification
molecular Structure
Palmitoylated pentapeptide signal sequence
stability
Stable under refrigerated conditions
Analytical Validation and Quality Assurance
- High-performance liquid chromatography purity testing
- Molecular identity confirmation
- Peptide structural integrity verification
- Batch-to-batch consistency validation
- Stability and formulation compatibility testing
Frequently Asked Questions
Matrixyl® is studied for extracellular matrix signaling, dermal fibroblast communication, and collagen-related pathway research.
Palmitoyl Pentapeptide-4 is a synthetic lipopeptide signal sequence derived from extracellular matrix protein fragments.
CAS 214047-00-4 uniquely identifies Matrixyl®, ensuring precise chemical identification and reproducibility in scientific research.
Yes. Matrixyl® is widely used in in-vitro studies examining ECM signaling, fibroblast communication, and peptide–cell interactions.
Matrixyl® is commonly used in molecular biology, cosmetic peptide research, ECM signaling studies, and topical formulation research.
The 200mg format allows extensive formulation testing and repeated laboratory experiments without frequent reordering.
Matrixyl® should be stored refrigerated at 2–8°C and protected from light and moisture.
BioPeptides provides high-purity research peptides with verified documentation and reliable supply for laboratory and cosmetic research.
