
MOTS-c 10mg
CAS: 1627580-64-6
MOTS-c 10mg by BioPeptides is a high-purity research-grade mitochondrial-derived peptide developed for advanced laboratory studies of mitochondrial signaling, cellular metabolism, and adaptive stress-response pathways. Produced using precision solid-phase peptide synthesis and purified to ≥99% HPLC, this peptide offers strong molecular stability and reproducibility. Identified by CAS 1627580-64-6, MOTS-c is widely used in controlled in-vitro research across Europe and the United States.
$295.00
Research Use Only
Research Overview
MOTS-c is a mitochondrial-encoded peptide used in laboratory research to investigate metabolic regulation and mitochondrial signaling pathways.
Researchers study MOTS-c to understand how mitochondrial peptides influence cellular metabolism and adaptive stress responses.
The peptide provides a framework for examining mitochondrial-to-nuclear signaling mechanisms.
MOTS-c contributes to broader investigations into mitochondrial biology and metabolic pathway regulation.

Scientific Background
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is encoded within mitochondrial DNA rather than nuclear DNA.
It belongs to a class of molecules known as mitochondrial-derived peptides (MDPs).
Researchers study MOTS-c for its involvement in metabolic signaling, stress-response pathways, and mitochondrial communication.
Its mitochondrial origin makes it valuable for studying retrograde signaling between mitochondria and the cell nucleus.

Mechanistic Research Perspective
- Mitochondrial-to-nuclear signaling pathway investigation
- Cellular metabolism and energy-regulation research
- Adaptive stress-response signaling studies
- Mitochondrial peptide communication analysis
- Metabolic signaling cascade research

Primary Research Applications
Mitochondrial Communication Research: MOTS-c is used to study retrograde signaling pathways through which mitochondria communicate with nuclear gene networks.
Cellular Metabolism Studies: Researchers investigate how MOTS-c influences cellular energy balance and metabolic regulation.
Stress-Response Pathway Analysis: The peptide supports laboratory research examining cellular adaptation to metabolic or environmental stress.
Mitochondrial Biology Research: MOTS-c enables exploration of mitochondrial-encoded peptides and intracellular communication mechanisms.
In-Vitro Cellular Research: The peptide is widely used in cell-based research models analyzing metabolic and mitochondrial signaling pathways.
Molecular Characteristics
- Compound Name: MOTS-c
- CAS Number: 1627580-64-6
- Peptide Class: Mitochondrial-derived peptide (MDP)
- Form: Lyophilized peptide powder
- Purity: ≥99% HPLC verified
- Unit Size: 10 mg research peptide
Stability Profile and Storage Recommendations
- Store lyophilized peptide at −20°C
- Protect from moisture and light exposure
- Avoid repeated freeze–thaw cycles
- Reconstitute using sterile laboratory-grade solvent
- Seal vial tightly after each use
Solubility and Preparation Considerations
- Soluble in sterile bacteriostatic water
- Compatible with buffered aqueous laboratory solutions
- Suitable for peptide research protocols
- Applicable in mitochondrial signaling assays
- Compatible with cell culture research systems
Technical Specifications
product Name
MOTS-c 10mg
brand
BioPeptides
cas
1627580-64-6
purity
≥99% (HPLC verified)
form
Lyophilized peptide powder
synthesis
Solid-phase peptide synthesis (SPPS)
analytical
HPLC and mass spectrometry verification
molecular Structure
Mitochondrial-derived signaling peptide
stability
Stable under −20°C storage conditions
Analytical Validation and Quality Assurance
- High-resolution HPLC purity testing
- Peptide identity verification
- Structural integrity analysis
- Batch-to-batch consistency validation
- Peptide stability testing
Frequently Asked Questions
MOTS-c is studied in laboratory research focused on mitochondrial signaling, metabolic regulation, and cellular stress-response mechanisms.
MOTS-c is encoded by mitochondrial DNA rather than nuclear DNA, making it valuable for studying mitochondrial-to-nuclear communication pathways.
CAS 1627580-64-6 uniquely identifies the peptide MOTS-c, ensuring accurate chemical documentation and reproducibility in research laboratories.
Yes. MOTS-c is commonly used in controlled in-vitro research involving mitochondrial function and metabolic signaling studies.
It is widely used in mitochondrial biology, metabolic research, molecular biology, and peptide signaling studies.
The 10mg format supports extended research programs, multiple assays, and improved cost efficiency for laboratories.
The peptide should be stored at −20°C in lyophilized form and protected from moisture and light.
BioPeptides provides high-purity peptides with verified CAS documentation and reliable international supply for research laboratories.
